Indocyanine green clearance as the prospective indicator of hepatocellular chemical toxicity
نویسندگان
چکیده
منابع مشابه
Chemical toxicity of indocyanine green damages retinal pigment epithelium.
PURPOSE To investigate the chemical toxicity of indocyanine green (ICG). METHODS Surface active and precipitating effects of ICG were quantitatively analyzed by determining bovine serum albumin dissolved or precipitated in the presence or absence of salt solutions. The effects of precipitation on serum and cytotoxicity were evaluated by measuring the viability of retinal pigment epithelium (R...
متن کاملClearance of indocyanine green as an index of liver function during cyclopropane anaesthesia and induced hypotension.
The rate of decrease in the plasma concentration of indocyanine green (ICG) following a bolus i.v. injection has been studied in two groups of patients before and during anaesthesia. In eight patients anaesthetized with nitrous oxide and oxygen, and who received a neuromuscular blocking drug, induction of anaesthesia was not associated with a significant change in ICG half-life (from 4.59 to 3....
متن کاملRetinal toxicity of indocyanine green in albino rabbits.
PURPOSE Intravitreal indocyanine green (ICG) is commonly used in vitreoretinal surgery. The purpose of this study was to evaluate possible toxicity of ICG in the retina of albino rabbits. METHODS Twenty-two albino rabbits were injected intravitreally with 0.1 mL ICG solution in one eye, and three rabbits were studied for the effects of 0.1 mL distilled water. All rabbits were injected intravi...
متن کاملRelation of the size of functional hepatic cell mass to the clearance of indocyanine green.
The correlation between fractional clearance (K) of indocyanine green (ICG) and size of hepatic cell mass altered by functional hepatectomy as well as the degree of hepatic damage induced by carbon tetrachloride (CCI 4) was investigated in the dog. Less than 20% functional hepatectomy produced only a minimal decrease in K of ICG probably due to the potential functional reserve of the liver, whi...
متن کاملIndocyanine green as a prospective sensitizer for photodynamic therapy of melanomas.
Spectroscopic, photochemical and biological properties of indocyanine green (ICG) are presented. Light over 800 nm is effectively absorbed by ICG. This property as well as photochemical behaviour of ICG make it a very suitable dye for photodynamic treatment of melanoma cells. Cytotoxicity of ICG itself and the effect of photodynamic therapy (PDT) were evaluated by following the growth of human ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1978
ISSN: 0016-5085
DOI: 10.1016/0016-5085(78)90659-5